I agree with Chris.
My general rule of thumb is to consider a change if the condition is temporary, like the "lazy eye." I've filled in a couple of missing baby teeth lately.
A while ago, I painted pro golfer Sam Snead when he was still living, and he had very crooked teeth. I didn't change them though, as it produced a very characteristic smile and expression, and it wouldn't have been a good portrait if I had. His son later wrote me that the family thought it was the best likeness of him they'd seen.
So you have to watch the "improvements."
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