A low vantage point might lend it a Sistine chapel-esque feeling, but you're still going to have some serious problems of distortion that would need to be addressed.
If you look up at the wall on which the painting will be hung, you'll notice the perspective - it can be quite dramatic. Picture it as a parallelogram - depending on how high up it is, and how sharp the viewing angle, the top of the shape could be as much as a foot smaller than the bottom.
If you don't take this into consideration then you'll wind up with huge feet and tiny heads. And then, even worse - what if the painting is visible from the stairs, and the upper level - looking back into the entry way? What a nightmare of conflicting vantage points.
If I were you, I'd urge them to pick a different spot.
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