A large part of learning the nature of one's paints has less to do with readily apparent chromatic differences (color, undertone, tinting strength, etc.) than how different pigments can be used in the construction of a sound painting.

Rates of drying, oil absorptive qualities, handling characteristics and relative transparency and opacity then become issues of importance which refines the painter's choice of materials in terms of their technical qualities and a chosen method of procedure.

So a given pigment is toxic? Certainly it's necessary to know this, and handle it accordingly. Portraitists in particular engage in placing small strokes of paint with an accuracy within a few thousandths of an inch to render "likeness". Most adults are quite capable of sitting to a formal dinner without getting food on their hands, faces, clothing, or on the person next to them. To be "safe" at the easel, don't eat the paint, but apply the same sensibilities you use at table, and don't get it all over you.

If the requirements of one's environment prohibit the casual and careless proximity of materials harmful to small children and pets when no semblance of ordered use or restrictions of care are in place, this precludes using all materials and paints associated with oil painting. Ingesting or wallowing in any of them will certainly cause injury.

Thank-you Richard!

The only time a family member of mine came close to ingesting paint with abandon was when my very long haired calico cat jumped on my palette fully laden with lead white and cadmiums.

It grabbed her screaming and hissing and dunked her into the bathtub before she could lick herself clean.

If I need it I use it. I do not eat it.

Precisely the point. Once it's mulled into paint, you really have to be oblivious and incredibly careless for even the most toxic pigments to affect you. In the dry state, that's another problem entirely. Back to Naples yellow, yes, other pigments in combination can approximate the color, but there's more to lead antimonate and its variants as pigments than just color.

RE/ the cat, ha ha ha ha! Sharon, you deserve a purple heart for that one! We once had a cat who was completely resistant to bathing. She was small. She was sweet tempered. She had the power and the attitude of a Bengal tiger in the bathtub. I gave up!